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This is especially effective when paired with a calorie-controlled diet and exercise

Or remains lethargic

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26 , 27 Thereby, this proof has to be a pleiotropic beneficial effect as the end result of the application of agents that were supposed to have the essential integrative role of the Selyes (still putative) mediator that integrates the adaptive bodily response to stress 22 , 25 whatever particular mechanism lies behind it

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