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Finally, it is notable that ALT activity has been the primary serum biomarker of liver injury since 1955 [76,77] but its metabolic and physiological roles in liver injury and disease are rarely considered, even though it is an important metabolic enzyme within the tissue [77]

4.2.4 FeMRI for early detection of cardiotoxicity Additionally, for anticancer drug-associated acute cardiac/renal injury, Fantian et al