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D.SulligerM.Ruiz-ReinaE.Rica-AlarcnR

J Drug Deliv Sci Technol 84:104473

The astaxanthin fed to salmon to enhance flesh coloration is in the non-esterified form [30] The predominance of evidence supports a de-esterification of fatty acids from the astaxanthin molecule in the intestine prior to or concomitant with absorption resulting in the circulation and tissue deposition of non-esterified astaxanthin

Metabolic Reprogramming of Hepatic Macrophages in Fatty Liver Disease In fatty liver disease, macrophages require metabolic reprogramming to meet the demands for energy and biosynthesis during the process of activation, while changes in metabolic patterns could switch the phenotype of macrophages

These alkaloids were shown to have diuretic, analgesic, anticancer, antipyretic, and antiemetic effects (Lata et al., 2016)