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J Genet Couns 2006
It's a potent modulator, not a direct activator
This ROS-driven cascade converges on microvascular dysfunctioncharacterized by dysregulated vasodilation, compromised endothelial barrier function, and increased vascular fragilityultimately manifesting as mucosal erosions and hemorrhage, the hallmark features of PHG [373]
A defining feature of OSA is intermittent hypoxemia, which contributes to the excessive production of reactive oxygen species (ROS) and the subsequent development of oxidative stress
That counted as one repetition
