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Given the increasing emphasis on the use of GLP-1 RAs in clinical practice, it is important that all members of the healthcare team, including pharmacy professionals, understand current recommendations and patient-specific considerations for use

If the patient experiences gastrointestinal adverse effects during dose escalation, uptitration can be delayed for an additional week [21]

This results in increased stimulation of anorexigenic POMC/CART neurones and decreased activity of orexigenic NPY/AgRP neurones, profoundly altering appetite signals (Trapp and Brierley 2022)

Libyan J Med 2014:9 online

Moreover, there was no difference in weight changes between exenatide and abiglutide, and both were shown to exhibit remarkable weight loss effects (174)