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(103(44)):e40364 doi:10.1097/MD.0000000000040364

Efficacy and safety of oral semaglutide in type 2 diabetes: a systematic review of real-world evidence

The STEP 1 trial, published in the New England Journal of Medicine, studied once-weekly semaglutide at 2.4mg in adults with overweight or obesity alongside lifestyle intervention

Additionally, to add context to GLP1RA targets, we added to the network interactors like GIPR, GCGR, GIP and GCG genes

Although BED and BN are disabling conditions, the limited treatment options highlight the need for identifying new pharmacological approaches such as glucagon-like peptide-1 receptor agonists (GLP-1RAs)
