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Supporting Collateral: Middle Market Formulary: The formularies indicate which brands are covered, the pharmacy tier, and if step therapy/prior authorization is required

Dr Johnson and colleagues noted, Further study is needed to better define the actual impact of GLP1RA on IBD-specific outcomes, ideally with more granular measures of disease activity.

Anhedonia and Depression on GLP-1s Because GLP-1s dampen dopamine release, there is a risk of dopamine blunting. This happens when the body doesnt release enough dopamine and causes emotional flatness

However, it is reasonable to assume that the increased risk of nausea and vomiting during anesthesia increases the risk of aspiration in patients taking these drugs

That is why injectable semaglutide is delivered under the skin rather than through the digestive tract