glp-1 receptor agonist with dpp-4 inhibitor combination not recommended inhibitors and GLP-1RAs: cardiovascular safety and benefits It's the first in a
Description
(82) showed that in vitro GLP-1 inhibited the ANG II-induced mesangial cell damage by suppressing superoxide-mediated nuclear factor-kB activation
& Roth, J

Cell Death Dis 9(2):212

Its central nervous system mechanism avoids GI effects almost entirely, substituting them for mild insomnia, dry mouth, and occasional dizziness

Jastreboff et al., NEJM, 2023