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If you're over 60, read our guide to GLP-1 risks for seniors for the full picture

Always follow the manufacturer's recommended titration schedule in the SmPC, and consider extending the time at lower doses if patients experience significant gastrointestinal symptoms

For adults, the common TGA pattern is this: these medicines may be used for chronic weight management in people with a BMI of 30 or more , or a BMI of 27 or more with at least one weight-related comorbidity such as hypertension, dyslipidaemia, obstructive sleep apnoea, cardiovascular disease, prediabetes or type 2 diabetes, depending on the product

doi: 10.3390/jcm12237502

however, electrical block of vagal afferents had variable clinical success, whereas direct stimulation of afferent endings at the gastric surface reduced satiety in some studies